Table 1. CMS46 hotspot mutation/variants in tumor types (n > 10 pts).

Tumor Type	Mutation (%)	Somatic (%)	Actionable (%)	Actionable w/o KRAS (%)	Total Pt #
Ovarian	81	48	16	10	58
Sarcoma	47	20	6	6	49
Colorectal	91	89	66	27	44
Lung	83	74	54	46	35
Head & Neck	72	49	15	15	39
Breast	80	70	43	43	30
Esophageal	79	57	18	18	28
Kidney	57	30	4	4	23
Gastric	76	67	19	19	21
Melanoma	87	80	80	80	15
Prostate	57	36	7	7	14
Liver	57	43	14	14	14
Pancreatic	100	100	85	23	13
Endometrial	89	78	39	33	18
Neuroendocrine	72	26	9	9	11
Thyroid	73	64	64	55	11