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A–D. 14-3-3σ protein levels were detected by western blotting in cells transfected with 14-3-3σ expressing plasmid or siRNA. 14-3-3σ overexpression enhanced the sensitivity of TC cells to PYM and cDDP with reduction of IC50 values, but 14-3-3σ knockdown attenuated the chemo-sensitivity of TC cells with increase of IC50 values detected by MTS proliferation assays. *p < 0.05, **p < 0.01.
