Table 2. Univariate and Multivariate Analysis of Variables Associated With DFS in Patients Submitted to an R0 Resection.
Median Survival (years) | |||||||
---|---|---|---|---|---|---|---|
Variable | No. of Patients | Median | Range |
P (univariate) |
P (multivariate) |
Hazard Ratio | 95% CI |
Tumor size | |||||||
≤ 3cm | 33 | > 3.20 | 0.08–4.92 | 0.028 | 0.732 | 0.864 | 0.373 to 1.998 |
> 3cm | 38 | 1.25 | 0.17–4.25 | ||||
Tumor stage | |||||||
T1/T2 | 43 | > 3.04 | 0.17–4.92 | 0.032 | 0.200 | 0.569 | 0.240 to 1.348 |
T3/T4 | 28 | 1.25 | 0.08–4.25 | ||||
Regional lymph nodes positive | |||||||
No | 51 | 3.08 | 0.17–4.92 | 0.072 | 0.702 | 0.857 | 0.388 to 1.892 |
Yes | 20 | 1.00 | 0.08–4.00 | ||||
TNM stage | |||||||
I/II | 25 | > 3.36 | 0.17–4.92 | 0.028 | 0.830 | 0.896 | 0.330 to 2.436 |
III/IV | 46 | 1.25 | 0.08–4.25 | ||||
PRR11 | |||||||
Negative | 16 | > 4.26 | 0.08–4.92 | < 0.001 | 0.001 | 0.129 | 0.037 to 0.446 |
Positive | 55 | 1.71 | 0.08–4.00 | ||||
CA199 levels | |||||||
Low | 16 | 1.83 | 0.42–4.92 | 0.054 | 0.420 | 0.759 | 0.388 to 1.483 |
High | 55 | 1.00 | 0.08–4.00 |