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. 2015 May 12;6(24):20540–20554. doi: 10.18632/oncotarget.4110

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Copyright: © 2015 Shi et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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A. BALB/c mice were subcutaneously injected with control or stable Dragon knockdown (shDragon) CT26.WT cells. Mice were sacrificed at day 31 after cell injections. Xenograft tumors were isolated. B. BALB/c mice were subcutaneously injected with control or stable Dragon knockdown (shDragon) CT26.WT cells; and C57BL/6 mice were subcutaneously injected with control or stable Dragon knockdown (shDragon) CMT93 cells. Tumor sizes were measured at days 7, 10, 13, 16, 19, 22, 25, 28 and 31 after injections (n = 6). C. BALB/c mice were subcutaneously injected with Dragon overexpression (oeDragon) or control CT26.WT cells. Mice were sacrificed at day 22 after cell injections. Xenograft tumors were isolated. D. BALB/c mice were subcutaneously injected with Dragon overexpression (oeDragon) or control CT26.WT cells. Tumor sizes were measured at days 7, 10, 13, 16, 19 and 22 after injections (n = 6). *P < 0.05; * P < 0.01.