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. 2015 May 13;6(24):20672–20684. doi: 10.18632/oncotarget.3967

Figure 4. S100P is required for SOX9-induced metastasis and invasion of colon cancer cells.

Figure 4

A. Assessment of the influence of S100P expression on SOX9-induced metastasis and invasion using established stable SOX9 overexpression (HCT116-SOX9(+)) and SOX9 overexpression plus S100P knockdown (HCT116-SOX9(+)/S100P(−)) cell lines by Transwell and Borden chambers. B. Comparison of the average number of cells penetrating the artificial basement membrane in the migration and invasion assays described in A. *P < 0.05, **P < 0.01, and ***P < 0.001. C. Western blot analysis of the role of S100P in the downstream signaling pathway of SOX9.