Figure 1. CUEDC2 is down-regulated in lung adenocarcinoma cell lines and lung adenocarcinoma tissues.
A. Western blotting analysis of CUEDC2 protein expression in primary lung adenocarcinoma (T) and paired normal lung (N) tissues from the same patient. B. CUEDC2 mRNA levels in lung adenocarcinomas (tumor, T) and matched normal lung tissue (N) from the same patient were analyzed using quantitative real-time PCR (qRT–PCR). The CUEDC2 expression levels were normalized to that of β-actin, the internal control. C. Western blotting analysis of CUEDC2 protein expression in A549, PC-9 H322, H1299, and SPC-A1 cells, indicating that CUEDC2 protein levels in lung cancer cells are lower than that in 16HBE cells. D. The expression of CUEDC2 mRNA in 16HBE and lung adenocarcinoma cell lines (A549, PC-9 H322, H1299, and SPC-A1) was analyzed using qRT–PCR.