Table 2. Sequencing results for rapamycin pool.
gene | position | alternate reads/ total reads | AC | p-value (AC) | GL-AC | p-value (GL-AC) | mutation | |
---|---|---|---|---|---|---|---|---|
1 | FPR1 | chrXIV:372100 | 38/63 | 3 | 1.40E-09 | 3 | 0.002 | F43I, F43L |
2 | MZM | chrIV:1436553 | 38/177 | 1 | 1 | 1 | 1 | A113S |
3 | DCR2 | chrXII:847561 | 33/156 | 1 | 1 | 1 | 1 | G522R |
4 | ITC1 | chrVII:258208 | 44/212 | 1 | 1 | 1 | 1 | R168C |
5 | ARO2 | chrVII:226630 | 26/136 | 1 | 1 | 1 | 1 | P78S |
: | : | |||||||
: | : | |||||||
: | : | |||||||
16 | TOR1 | chrX:565331 | 33/204 | 1 | 1 | 1 | 1 | S1972R |
: | : | |||||||
: | : | |||||||
: | : | |||||||
50 | NTE1 | chrXIII:157425 | 12/221 | 1 | 1 | 1 | 1 | D278E |