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. 2015 Oct 27;112(45):13862–13867. doi: 10.1073/pnas.1512959112

Fig. S3.

Fig. S3.

Orientation of A-site decoding center nucleotides upon HigB binding to the 70S. (A) Comparison of 16S rRNA residues A1492 and A1493 when HigB binds to the 70S trapped in a precleavage state (tan), in a postcleavage state (pink), when no A-site ligand is bound (PDB code 4V6G; blue) and when cognate A-site tRNA is bound (PDB code 4V51; gray). (B) Location of A1492 and A1493 with respect to HigB in a precleavage state and in a postcleavage state and their proximity to loop 3 of HigB. (C) Orientation of 16S rRNA residues G530 and C1054 in precleavage and postcleavage state structures of 70S-HigB compared with when the ribosomal A site contains cognate tRNA (gray) or is empty (blue).