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Clinicopathological comparison of WDNEC and PDNEC
| WDNEC (n = 4) | PDNEC (n = 7) | |
|---|---|---|
| Vascularity in pancreas tumor | ||
| Yes (%) | 50 % (2/4) | 0 % (0/7) |
| Ki67 labeling index | ||
| Median (range) | 46.3 % (40–53 %) | 85 % (54–95 %) |
| Rb immunopositivity | 100 % (4/4) | 14 % (1/7) |
| KRAS mutation | 0 % (0/4) | 86 % (6/7) |
| Response rate of platinum-based regimen | 0 % (0/2) | 100 % (4/4) |
| Prognosis | ||
| Median | 227 days | 186 days |
WDNEC well-differentiated NEC, PDNEC poorly differentiated NEC
