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. 2015 Nov 7;29(11):953–962. doi: 10.1007/s40263-015-0291-6

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© The Author(s) 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Mean change from baseline in WFIRS-P scores at Visit 10 (last observation carried forward) by treatment response to GXR treatment; full analysis set (GXR all-active group). Responders are defined as subjects with ADHD-RS-IV Total score reduction from baseline ≥30 % and a CGI-I score of 1 or 2. WFIRS-P Weiss Functional Impairment Rating Scale–Parent Report, GXR guanfacine extended release, ADHD-RS-IV Attention-Deficit/Hyperactivity Disorder, CGI-I Clinical Global Impressions–Improvement Scale. ***P <0.001