Table 1.
Characteristics of cases and controls
| Characteristic | Asthma | Asthma with rhinitis | Rhinitis | Controls |
p One way ANOVA |
|---|---|---|---|---|---|
| No | 271 | 866 | 415 | 275 | |
| Femalea | 210 (78) | 563 (65) | 216 (52) | 155 (56) | <0.001 |
| Age (years)b | 30 (29–30) | 30 (30–31) | 32 (31–33) | 33 (32–34) | <0.001 |
| BMI (kg/m2)b | 25 (24–26) | 25 (25–26) | 25 (25–26) | 25 (25–26) | NS |
| FEV1,% of predictedb | 94.9 (93.2–96.6) | 93.7 (92.8–94.7) | 100.0 (98.8–101.1) | 103.0 (101.5–104.4) | <0.001 |
| FVC,% of predictedb | 97.2 (95.5–98.8) | 96.2 (95.3–97.0) | 97.6 (96.2–98.9) | 97.0 (94.7–99.3) | NS |
| FEV1/FVCb | 0.82 (0.81–0.83) | 0.81 (0.80–0.81) | 0.84 (0.83–0.84) | 0.83 (0.82–0.83 | <0.001 |
| logRDRb | 0.77 (0.70–0.84 | 0.88 (0.84–0.92) | 0.30 (0.25–0.35) | 0.16 (0.07–0.24) | <0.001 |
| CC genotypea | 161 (61) | 519 (61) | 243 (59) | 167 (64) | NS |
| CG genotypea | 97 (37) | 297 (35) | 148 (36) | 87 (33) | NS |
| GG genotypea | 5 (2) | 39 (5) | 19 (5) | 8 (3) | NS |
| Serum YKL-40 (µg/L)c | 40 (14–193) | 40 (10–280) | 38 (11–315) | 43 (14–195) | NS (Kruskal-Wallis) |
RDR, response dose-ratio; NS, non-significant.
a
Values are number (%).
b
Values are median (95% CI).
c
Values are range (min–max).