Figure 5. 3-day treatment with ASC-CM showed reduced GFAP expression in the spinal cords of SOD1G93A mice after disease onset.
Figure SOD1G93A mice with disease onset were given ASC-CM or vehicle for 3 days. Spinal cords were removed for immunoblot. Actin expression levels remained constant in all groups and were used as internal loading controls. (A) Representative immunoblots and (B) band quantitation demonstrated a decrease in spinal cord GFAP expression after 3-day ASC-CM treatment as compared to vehicle. Experiments were completed in triplicate with n = 3 per group. *p < 0.05; ***p < 0.005.