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Capsid particles stay intact during the 2-h-long trypsin digestion. A and B, dynamic light scattering measurements of the Z-average diameter (A) and the light scattering intensity (derived count rate) (B) for a sample of 10 μm Cp183-WT (black dots) and EEE (gray dots) that was digested with 0.12 μm trypsin. Each data point represents one measurement that is the average of 10 runs.
