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. 2015 Nov 20;5:16973. doi: 10.1038/srep16973

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Ir780-labeled DMCs (red) injected intravenously were tracked during the 8 days. After surgical removal of the ileocecal region, samples were cut on a cryostat, counterstained with DAPI (blue), and analyzed under a confocal microscope. Labeled cells migrated towards the inflamed ileocecal region (A), but rarely to the non-inflamed bowel and other organs (kidney, lung, and liver, (B) Ir780-labeled DMCs were observed predominantly in the abscess formed around the CLP site. Images represent 3 independent experiments.