FIG. 3.

MNCs improved neurogenesis and angiogenesis at day 28 after ICH. (A) The representative photomicrographs showing the neuroblasts in the striatum near the subventricular zone. Only cells with the double doublecortin (DCX; green) and nuclear marker 4′,6-diamidino-2-phenylindole (DAPI) staining were enumerated as DCX-positive cells (arrows). The subventricular zone is shown as the area between the two broken yellow lines. Bar graph on the right shows the number of DCX-positive cells in the striatum in saline- and MNC-treated rats. ^†P < 0.05, compared with the saline-treated group. Magnification: 200×. n = 4 per group. (B) Representative photomicrographs showing CD31-labeled blood vessels (red) at day 28 after stroke. Bar graphs on the right show the vessel numbers in saline- and MNC-treated rats. ^†P < 0.05, compared with saline-treated group. Magnification: 200×. n = 4 per group. LV, lateral ventricle. Color images available online at www.liebertpub.com/scd