Table 1.
Characteristics of the 694 patients with NPC
| Variable | No. (%) | LWL/MWL (weight loss <10 %) | HWL (weight loss ≥10 %) | P value |
|---|---|---|---|---|
| Age, years | 0.414 | |||
| <50 | 473 (68.2) | 350 (74.0) | 123 (26.0) | |
| ≥50 | 221 (31.8) | 157 (71.0) | 64 (29.0) | |
| Sex | 0.001 | |||
| Male | 517 (74.5) | 394 (76.2) | 123 (23.8) | |
| Female | 177 (25.5) | 113 (63.8) | 64 (36.2) | |
| T classification | 0.001 | |||
| T1–2 | 313 (45.1) | 248 (79.2) | 65 (20.8) | |
| T3–4 | 381 (54.9) | 259 (68.0) | 122 (32.0) | |
| N classification | 0.009 | |||
| N0 | 196 (28.2) | 157 (80.1) | 39 (19.9) | |
| N1–3 | 498 (71.8) | 350 (70.3) | 148 (29.7) | |
| Clinical stage | <0.001 | |||
| I + II | 235 (33.9) | 191 (81.3) | 44 (18.7) | |
| III + IV | 459 (66.1) | 316 (68.8) | 143 (31.2) | |
| Chemotherapy | <0.001 | |||
| No | 215 (31.0) | 186 (86.5) | 29 (13.5) | |
| Yes | 479 (69.0) | 321 (67.0) | 158 (33.0) | |
| White blood cell count, k/μL | 0.035 | |||
| <6.9 | 339 (48.8) | 260 (76.7) | 79 (23.3) | |
| ≥6.9 | 355 (51.2) | 247 (69.6) | 108 (30.4) | |
| NLR | 0.171 | |||
| <2.3 | 360 (51.9) | 271 (75.3) | 89 (24.7) | |
| ≥2.3 | 334 (48.1) | 236 (70.7) | 98 (29.3) | |
| Blood platelet count, k/μL | 0.221 | |||
| <221 | 342 (49.3) | 257 (75.1) | 85 (24.9) | |
| ≥221 | 352 (50.7) | 250 (71.0) | 102 (29.0) | |
| PLR | 0.347 | |||
| <120.7 | 347 (50.0) | 259 (74.6) | 88 (25.4) | |
| ≥120.7 | 347 (50.0) | 248 (71.5) | 99 (28.5) | |
| Hemoglobin, g/L | 0.283 | |||
| <144 | 335 (48.3) | 251 (74.9) | 84 (25.1) | |
| ≥144 | 359 (51.7) | 256 (71.3) | 103 (28.7) | |
| PNI | 0.301 | |||
| <55.0 | 345 (49.7) | 246 (71.3) | 99 (28.7) | |
| ≥55.0 | 349 (50.3) | 261 (74.8) | 88 (25.2) | |
| Alkaline phosphatase, U/L | 0.337 | |||
| <68 | 340 (49.0) | 254 (74.7) | 86 (25.3) | |
| ≥68 | 354 (51.0) | 253 (71.5) | 101 (28.5) | |
| Bilirubin, μmol/L | 0.859 | |||
| <4.1 | 345 (49.7) | 251 (72.8) | 94 (27.1) | |
| ≥4.1 | 349 (50.3) | 256 (73.4) | 93 (26.6) | |
| Albumin, g/L | 0.399 | |||
| <45.4 | 338 (48.7) | 242 (71.6) | 96 (28.4) | |
| ≥45.4 | 356 (51.3) | 265 (74.4) | 91 (25.6) | |
| Globulin, g/L | 0.009 | |||
| <30.2 | 339 (48.8) | 263 (77.6) | 76 (22.4) | |
| ≥30.2 | 355 (51.2) | 244 (68.7) | 111 (31.3) | |
| Body mass index, kg/m2 | 0.040 | |||
| Underweight (<18.5) | 66 (9.5) | 57 (86.4) | 9 (13.6) | |
| Normal weight (18.5–22.99) | 305 (43.9) | 225 (73.5) | 80 (26.2) | |
| Overweight (23.0–27.49) | 273 (39.3) | 192 (70.3) | 81 (29.7) | |
| Obese (≥27.5) | 50 (7.3) | 33 (66.0) | 17 (34.0) |
NLR neutrophil/lymphocyte ratio, PLR platelet/lymphocyte ratio, PNI prognostic nutritional index, LWL low weight loss, MWL moderate weight loss, HWL high weight loss