Table 3.
Effects of thoracic epidural analgesia on oxygenation and pulmonary shunt fraction variables during OLV
| Median of Means (Range) | |||||
|---|---|---|---|---|---|
| All available data | No. of comparisons | TEA group | GA group | WMD (95 % CI) | P value |
| During two-lung ventilation | |||||
| PaO2 (mmHg) | 13 | 382.42(205.00 to 85.00) | 377.92(191.0 to 453.00) | 6.29 [0.04 to 12.17] | 0.35 |
| PaCO2 (mmHg) | 10 | 39.67 (32.50 to 37.6) | 40.23 (35.60 to 37.40) | −0.21 [−1.11 to 0.68] | 0.64 |
| PvO2 (mmHg) | 7 | 51.50(48.00 to 55.0) | 51.62(48.0 to 53.30) | 0.27 [−1.51 to 2.06] | 0.76 |
| Qs/Qt (%) | 13 | 14.80 (4.90 to 22.50) | 15.50 (3.95 to 21.60) | 0.02[−0.47 to 0.50] | 0.95 |
| SvO2 (%) | 4 | 85.37(83.30 to 87.10) | 86.68(84.90 to 88.20) | −1.22[−2.36 to −0.07] | 0.58 |
| SaO2 (%) | 4 | 99.75(99.70 to 99.90) | 99.45(99.00 to 99.90) | −0.06[−0.08 to −0.04] | 0.30 |
| PH | 4 | 7.43 (7.42 to 7.43) | 7.44 (7.43 to 7.44) | −0.01 [−0.02 to 0.00] | 0.21 |
| Paw (cmH2O) | 4 | 18.63 (17.00 to 20.00) | 19.03 (17.00 to 21.40) | −0.24 [−1.14 to 0.66] | 0.60 |
| During one-lung ventilation within 30 min | |||||
| PaO2 (mmHg) | 10 | 166.90(118.00 to 211.00) | 171.2(122.00 to 201.00) | −16.52[−21.98 to -11.05] | <0.01 |
| PaCO2 (mmHg) | 10 | 37.12 (36.10 to 44.20) | 36.85(34.20 to 42.20) | 0.29 [−0.53 to 1.10] | 0.49 |
| PvO2 (mmHg) | 7 | 47.78(44.90 to 54.00) | 46.14(44.50 to 51.00) | 1.13 [−0.50 to 2.76] | 0.17 |
| Qs/Qt (%) | 10 | 33.32 (27.30 to 39.50) | 32.77 (26.70 to 40.60) | 2.53 [1.35 to 3.72] | <0.01 |
| SvO2 (%) | 4 | 80.53(78.30 to 82.60) | 81.58(78.40 to 84.20) | −1.13[−2.74 to 0.48] | 0.17 |
| SaO2 (%) | 4 | 97.98(96.80 to 99.30) | 97.65(97.30 to 98.00) | 0.74[0.33 to 1.15] | <0.01 |
| PH | 4 | 7.43 (7.42 to 7.44) | 7.44 (7.42 to 7.46) | −0.01 [−0.02 to 0.001] | 0.41 |
| Paw (cmH2O) | 4 | 28.00 (23.00 to 32.50) | 27.00 (24.00 to 30.90) | 1.95 [1.61 to 2.28] | <0.01 |
| One-lung ventilation more than 30 min | |||||
| PaO2 (mmHg) | 11 | 162.27(117.00 to 203.00) | 168.72(148.00 to 221.00) | −14.23[−20.81 to -7.65] | <0.01 |
| PaCO2 (mmHg) | 11 | 36.61 (33.90 to 44.60) | 36.78 (35.00 to 44.20) | −0.22 [−0.96 to 0.53] | 0.57 |
| PvO2 (mmHg) | 6 | 44.70(42.60 to 46.10) | 44.98(43.40 to 46.60) | −0.61[−2.23 to 1.02] | 0.46 |
| Qs/Qt (%) | 12 | 34.40 (33.60 to 42.70) | 32.67 (32.10 to 40.90) | 2.77 [1.81 to 3.74] | <0.01 |
| SvO2 (%) | 6 | 79.33(77.40 to 81.10) | 81.97(78.50 to 83.90) | −2.39[−3.73 to −0.99] | <0.01 |
| SaO2 (%) | 6 | 97.68(96.60 to 98.10) | 98.20(97.20 to 99.00) | −0.63[−1.23 to −0.04] | 0.04 |
| PH | 6 | 7.43 (7.43 to 7.44) | 7.44 (7.41 to 7.46) | 0.00 [−0.01 to 0.01] | 0.50 |
| Paw (cmH2O) | 6 | 26.80 (24.00 to 32.50) | 26.72 (24.00 to 31.40) | 0.87 [0.54 to 1.20] | <0.01 |
| Re-two ventilation | |||||
| PaO2 (mmHg) | 7 | 322.28(173.00 to 482.00) | 307.28(168.00 to 407.00) | 11.54[−4.25 to 27.34] | 0.15 |
| PaCO2 (mmHg) | 3 | 37.8 (34.00 to 46.10) | 35.6 (34.90 to 36.90) | −0.60 [−3.03 to 1.83] | 0.63 |
| PvO2 (mmHg) | 5 | 47.82(43.00 to 50.00) | 48.68(46.20 to 51.00) | 0.06[−2.24 to 2.36] | 0.96 |
| Qs/Qt (%) | 6 | 18.55(15.30 to 24.50) | 20.15(15.50 to 24.80) | −1.27 [−2.73 to 0.20] | 0.09 |
| SvO2 (%) | 2 | 81.90(81.50 to 82.30) | 85.30(85.30 to 85.30) | −3.62[−6.28 to −0.95] | 0.80 |
| SaO2 (%) | 2 | 99.75(99.70 to 99.80) | 99.00 (99.00 to 99.00) | 0.75[0.52 to 0.98] | 0.67 |
| PH | 2 | 7.42 (7.41 to 7.42) | 7.42 (7.42 to 7.42) | 0.00 [−0.03 to 0.02] | 0.77 |
| Paw (cmH2O) | 2 | 19.00 (18.00 to 20.00) | 18.00 (18.00 to 18.00) | 0.95 [−0.81 to 2.71] | 0.29 |
Data were presented as Mean and rang in bracket