Table 2.
Histological diagnosis of specimen A and B resulted from the routine analysis and from the revision analysis performed by an experienced gynecologic pathologist
| Hystological Diagnosis | Specimen A N (%) | Specimen B N (%) | ||||
|---|---|---|---|---|---|---|
| Routine Analysis | Revision Analysisa | p Value | Routine Analysis | Revision Analysisa | p Value | |
| Negative | 18 (7.2) | 40 (15.9) | .34 | 35 (13.9) | 51 (20.3) | .03 |
| Cervicites / Metaplasia | 116 (46.2) | 96 (38.2) | 95 (37.8) | 102 (40.6) | ||
| CIN1 / Koilocytosis / Condylomatosis | 71 (28.3) | 65 (25.9) | 73 (29.1) | 52 (20.7) | ||
| CIN2 | 20 (8.0) | 14 (5.6) | 24 (9.6) | 10 (4.0) | ||
| CIN3 | 26 (10.4) | 36 (14.3) | 24 (9.6) | 36 (14.3) | ||
aRevision analysis: analysis performed by experienced pathologist. In uncertain cases immunohistochemical stains were used, particularly, antibody against ki67 to evaluate the proliferative activity and p16 protein expression to determine the different degrees of CIN