Skip to main content
. 2015 Sep 29;24(24):7087–7096. doi: 10.1093/hmg/ddv408

Figure 2.

Figure 2.

Loss of MSH3 reduces paternally and maternally transmitted intergenerational expansions. The number of expansions, contractions and unchanged alleles seen on transmission of a PM allele with ∼140 repeats from WT, Msh3+/− and Msh3−/− parents was determined in the progeny of 2- to 6-month-old (A) and 7- to 12-month-old (B) males and in the progeny of 2- to 6-month-old (C) and 7- to 12-month-old (D) females. The error bars represent the 95% confidence intervals. The allele classes that are significantly different from WT animals are marked with asterisks (*P < 0.05; **P < 0.01; ***P < 0.001).