Figure 2.

CDCN’s research model. The CDCN has taken a four-step approach to drive forward “omics” research: 1a) The CDCN identified and connected the research community and (1b) provided supportive resources to patients and loved ones. Then, the CDCN turns to the research community (2a) and patient community (2b) to prioritize key research studies into an International Research Agenda as well as collect and centrally store clinical data and tissue samples. With the top priority projects identified, the CDCN solicits funding from patients and loved ones for specific projects. Then, the CDCN provides two mechanisms for funding: (3a) investigator-initiated research grants through traditional requests for proposals and (3b) strategically directed research grants where the DRO recruits the top experts within the community or outside of the community to do the studies. 4) Pharmaceutical companies are more eager to contribute tissue samples and funding for clearly defined projects with the greatest likelihood of return.