Table 2.
Cox Regression Model for 30‐Day Case Fatality after Intracerebral Hemorrhage (n = 1,547)
| Factor | Univariate HR (95% CI) | p | Multivariate HR (95% CI) | p |
|---|---|---|---|---|
| Age, per year | 1.016 (1.008–1.024) | <0.001 | 1.020 (1.012–1.029) | <0.001 |
| Male sex | 1.029 (0.886–1.196) | 0.707 | 1.172 (1.005–1.366) | 0.043 |
| ICH volume, per log transformed ml | 1.889 (1.766–2.020) | <0.001 | 1.429 (1.327–1.539) | <0.001 |
| Infratentorial location | 1.020 (0.839–1.241) | 0.842 | 1.386 (1.125–1.707) | 0.002 |
| Intraventricular extension | 3.139 (2.672–3.687) | <0.001 | 1.682 (1.410–2.007) | <0.001 |
| Baseline INR, per unit | 1.108 (1.071–1.147) | <0.001 | 1.052 (1.012–1.094) | 0.010 |
| Glasgow Coma Scale, per point | 0.822 (0.808–0.836) | <0.001 | 0.878 (0.860–0.896) | <0.001 |
| Combination of FFP and PCC | Reference | Reference | ||
| PCC alone | 1.407 (0.989–2.002) | 0.058 | 1.445 (1.014–2.058) | 0.041 |
| FFP alone | 1.849 (1.291–2.649) | <0.001 | 1.344 (0.934–1.934) | 0.112 |
| No reversal | 3.182 (2.248–4.505) | <0.001 | 2.540 (1.784–3.616) | <0.001 |
CI = confidence interval; FFP = fresh frozen plasma; HR = hazard ratio; ICH = intracerebral hemorrhage; INR = international normalized ratio; PCC = prothrombin complex concentrate.