Table 2.
Multivariate analyses for current doctor-diagnosed asthma, atopic and nonatopic asthma at 8 years of age
| Current asthma | Atopic Asthma | Nonatopic asthma | |
|---|---|---|---|
| Risk factor | aOR (95% CI) | aOR (95% CI) | aOR (95% CI) |
| Normal BMI | 1 ref. | 1 ref. | 1.ref |
| Early high BMI | 0.7 (0.3–1.5) | 0.8 (0.3–2.1) | 0.4 (0.1–1.8) |
| Late high BMI | 1.1 (0.5–2.2) | 1.1 (0.4–2.5) | 1.5 (0.5–4.6) |
| Persistently high BMI | 2.9 (1.3–6.4) | 4.7 (2.0–11.0) | * |
| Atopic heredity (mother or father with asthma, eczema or rhinitis) | 1.5 (0.9–2.5) | 1.2 (0.7–2.2) | 2.5 (1.01–6.4) |
| Male gender | 1.4 (0.9–2.2) | 1.7 (0.9–3.0) | 1.1 (0.5–2.4) |
| Maternal medication during pregnancy | 1.4 (0.9–2.2) | 1.3 (0.8–2.2) | 1.8 (0.9–3.9) |
| Gestational age <37 weeks | 1.0 (0.4–2.7) | 1.1 (0.3–3.6) | 1.9 (0.5–7.9) |
| Caesarean section | 1.3 (0.7–2.3) | 1.3 (0.6–2.6) | 1.2 (0.4–3.1) |
| Small for gestational age | 2.6 (0.9–8.2) | 4.2 (1.3–14.2) | 0.8 (0.06–11.2) |
| Large for gestational age | 0.2 (0.03–1.6) | 0.3 (0.04–2.4) | * |
| Treatment with antibiotics during the first week | 2.8 (1.4–5.9) | 3.5 (1.5–8.0) | 2.2 (0.6–9.0) |
| Doctor-diagnosed food allergy during the first year | 5.6 (2.9–10.9) | 8.0 (3.9–16.3) | 1.0 (0.1–8.3) |
| Eczema during the first year | 1.5 (0.9–2.4) | 2.2 (1.3–3.8) | 0.6 (0.2–1.6) |
| Recurrent wheeze during the first year | 4.4 (2.4–8.0) | 2.7 (1.2–6.0) | 10.8 (4.6–25.8) |
| Introduction of fish before 9 months of age | 0.6 (0.4–0.97) | 0.5 (0.3–0.96) | 0.7 (0.3–1.9) |
| Fish once a month or more at one year of age | 0.9 (0.4–1.9) | 0.6 (0.3–1.4) | * |
| Maternal obesity | 1.3 (0.7–2.6) | 1.5 (0.7–3.2) | 0.8 (0.2–3.7) |
| Daily outdoor activity at 12 months | |||
| Less than one hour | 1 ref. | 1 ref | 1 ref. |
| One to three hours | 2.4 (0.7–7.9) | 4.7 (0.6–35.4) | 1.4 (0.3–6.2) |
| More than three hours | 1.3 (0.3–5.0) | 2.0 (0.3–17.5) | 1.3 (0.2–7.6) |
| Rural living at 6 months | 0.9 (0.6–1.6) | 0.9 (0.5–1.8) | 0.8 (0.3–2.1) |
| Breastfeeding for 4 months or more | 0.8 (0.5–1.3) | 0.7 (0.4–1.4) | 1.0 (0.4–2.7) |
| Smoking during pregnancy | 1.3 (0.6–2.8) | 1.5 (0.7–3.6) | 0.5 (0.06–4.0) |
| Parental educational level (>12 years) at 6 months | 1.2 (0.7–1.9) | 0.9 (0.5–1.7) | 1.8 (0.7–4.3) |
Independent risk factors for current doctor-diagnosed asthma are in bold, as well as the independently significant aORs.
*
No OR is given due to too few subjects in this analysis with nonatopic asthma.