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IgG and IgM production are increased in IA patients but reduced in RP subjects. (A) Plasma IgG and IgM levels in HC, IT, IA, IC, and RP subjects were determined using ELISA. P-values less than 0.05 are shown. (B) IgG and IgM production levels in B cells stimulated with PWM for 3 or 7 days in vitro were determined using ELISA. The boxes represent the 5th, 25th, 75th, and 95th percentiles, and the solid line indicates the median value of each subset. *P < 0.05, **P < 0.01.
