Figure 1.

CD3⁻CD56^brightCD25⁺ dNK cells are preferentially recruited to the maternal/fetal interface in early human pregnancy. (a, b) Comparison of the percentage of CD25⁺ NK cells in pNK and dNK cells in early human pregnancy. CD56⁺ NK cells were gated on prior to analysis of CD25 expression by FCM. The percentage of CD25⁺ NK cells was determined. (c, d) Comparison of the cell subsets constituting CD25⁺, CD25⁻ or total immune cells from PBMC and DICs in early human pregnancy. Data represent the mean±standard error from ten independent experiments with ten deciduas. A representative image is shown. Data were analyzed using a paired t-test (b). ***P<0.001. DIC, decidual immune cell; dNK, decidual natural killer; PBMC, peripheral blood mononuclear cell; pNK, peripheral natural killer.