Table 4. Results of allelic association testing for physician-diagnosed asthma following severe RSV bronchiolitis in infancy including genotypes from the Exome Sequencing Project (ESP) as controls.
| RBEL European Americans: | RBEL African Americans: | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Position (hg19) | rsID | Gene | Alleles (A1/A2) | Freq A1 asthma cases | Freq A1 ESP | P-value ESP | Freq A1 asthma cases | Freq A1 ESP | P-value ESP |
| chr1:152283023 | NA | FLG | T/A | 0.013 | 0.0001 | 1.9x10-13 | 0 | 0 | NA |
| chr5:148206885 | rs1800888 | ADRB2 | T/A | 0.064 | 0.015 | 4.6x10-4 | 0 | 0.0032 | 0.58 |
| chr11:113076804 | rs35576001 | NCAM1 | A/G | 0.013 | 0.0006 | 5x10-5 | 0.021 | 0.027 | 0.74 |
| chr12:117768154 | rs76090928 | NOS1 | A/G | 0.013 | 0.004 | 0.23 | 0.011 | 0 | 2.3x10-11 |