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. 2015 Nov 20;10(11):e0142924. doi: 10.1371/journal.pone.0142924

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© 2015 Portale et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 2 — Egr-1 ^-/- and wild-type (WT) mice were treated with vehicle or FGF23. A. Serum 1,25(OH)₂D concentrations. B. Renal cyp27b1 and, C. Renal cyp24a1 mRNA abundance were quantitated by real-time PCR, normalized to that of gus mRNA, and expressed as a percent relative to vehicle-treated WT mice. Bars depict mean ± SEM (n = 8–10 mice/group) * P<0.05, compared to egr-1 ^-/- and WT mice treated with vehicle.