Table 2. MRP knock-out C. elegans mutants mortality expressed as percentage of dead worms and comparison between the mutants and the WT.
Mutant mrp-5 was tested as heterozygote, due to lethality of the mutation in homozygosis. Statistical significant differences appear highlighted, with negative values indicating statistically significant reductions in mortality from WT, and with positive values indicating statistically significant increases in mortality from WT.
| Significant Changes in % Mortality | ||||||||
|---|---|---|---|---|---|---|---|---|
| Strain | WT Mortality FKA | mrp-1 | mrp-2 | mrp-3 | mrp-4 | mrp-5 | mrp-6 | mrp-8 |
| B. ambifaria | 95 | NS | -27 | NS | NS | NS | NS | NS |
| B. anthina | 42 | 45 | 50 | NS | NS | 58 | NS | NS |
| B. arboris | 28 | 70 | 72 | 21 | NS | NS | 72 | 72 |
| B. cenocepacia | 64 | NS | 31 | NS | -45 | NS | 27 | NS |
| B. cepacia | 100 | -19 | NS | NS | -19 | NS | -15 | -18 |
| B. contaminans | 94 | NS | NS | -17 | -16 | NS | NS | NS |
| B. diffusa | 69 | NS | NS | NS | NS | NS | NS | -26 |
| B. dolosa | 31 | 33 | NS | 59 | NS | 48 | 49 | NS |
| B. latens | 42 | NS | NS | -34 | NS | 38 | NS | -28 |
| B. metallica | 100 | NS | NS | -13 | -17 | NS | NS | -10 |
| B. pseudomultivorans | 20 | NS | NS | NS | NS | 50 | NS | NS |
| B. pyrrocinia | 70 | NS | 21 | -44 | -35 | 26 | NS | 29 |
| B. seminalis | 64 | NS | NS | -44 | -31 | NS | NS | NS |
| B. stabilis | 100 | -9 | -47 | NS | NS | -10 | -63% | -77% |
| B. ubonensis | 52 | NS | 41 | NS | -24% | 38 | NS | 32 |
| B. vietnamiensis | 14 | NS | 40 | -12% | NS | 57 | 61 | 35 |
| B. lata | 18 | 38 | 64 | 27 | 42 | 70 | 54 | 53 |
| B. multivorans | 7 | 33 | 22 | 21 | 34 | 62 | 28 | 45 |
| Strain | WT Mortality SKA | mrp-1 | mrp-2 | mrp-3 | mrp-4 | mrp-5 | mrp-6 | mrp-8 |
| B. ambifaria | 6 | 61 | 67 | 30 | 28 | 75 | 71 | 58 |
| B. anthina | 91 | 9 | NS | -27 | -24 | NS | NS | NS |
| B. arboris | 46 | 53 | 54 | -35 | NS | NS | 50 | 51 |
| B. cenocepacia | 81 | NS | NS | NS | -77 | -65 | -24 | -54 |
| B. cepacia | 9 | 81 | 75 | NS | NS | 78 | 62 | 45 |
| B. contaminans | 47 | 30 | 26 | 49 | NS | NS | NS | NS |
| B. diffusa | 88 | NS | NS | NS | -25 | NS | NS | NS |
| B. dolosa | 13 | NS | 25 | NS | NS | 61 | 61 | 28 |
| B. latens | 22 | NS | 43 | -19 | -19 | 46 | NS | 42 |
| B. metallica | 100 | NS | NS | -14% | -8% | NS | NS | NS |
| B. pseudomultivorans | 11 | NS | NS | NS | NS | 30 | NS | NS |
| B. pyrrocinia | 5 | 53 | 61 | NS | NS | 64 | 57 | 46 |
| B. seminalis | 69 | 28 | NS | -50 | -67 | NS | NS | NS |
| B. stabilis | 100 | -90 | -58 | NS | NS | -55 | -60 | -84 |
| B. ubonensis | 83 | -60 | NS | -28 | -36 | NS | NS | NS |
| B. vietnamiensis | 46 | -44 | -39 | -43 | -44 | -34 | 50 | -41 |
| B. lata | 10 | NS | NS | NS | NS | 52 | NS | NS |
| B. multivorans | 3 | NS | 22 | NS | NS | 35 | 41 | NS |
NS = Not significant difference