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(Top) Schematic diagram of theranostic approach for osteoarthritis-type II collagen antibodies-targeted fluorescent nanosomes. These nanosomes bind on damaged cartilage in an OA animal model, providing a traceable fluorescent signal and delivering therapeutic agents.[2] (Bottom) In a spontaneous OA model in guinea pigs, older animal showed higher accumulation of immunoliposomes. Reproduced with permission from Elsevier. [3]
