Table 2.
Lower connectivity in smokers vs. never-smokers in a network connected to the right anterior insula
| Brain Region | BAa | # Voxb | % ROIc | Hemd | Clustere | xf | yf | zf |
p, FWE correctedg |
|---|---|---|---|---|---|---|---|---|---|
| OFC | 11 | 431 | 18 | R | 2108 | 12 | 20 | −32 | < 0.001 |
| IFC | 47 | 247 | 13 | R | |||||
| OFC | 11 | 213 | 9 | L | |||||
| Temporal Pole | 38 | 104 | 6 | R | |||||
| Anterior PFC | 10 | 102 | 3 | R | |||||
| Subgenual ACC | 25 | 81 | 19 | R | |||||
| Entorhinal Cortex | 34 | 79 | 20 | L | |||||
| Subgenual ACC | 25 | 40 | 9 | L | |||||
| Entorhinal Cortex | 28 | 31 | 7 | L |
a
Brodmann area
b
Number of voxels within each cluster
c
Percentage of brain region included in each cluster
d
Hemisphere: R, right, L, left
e
Cluster size; number of contiguous voxels with p < 0.05
f
x, y, and z coordinates in MNI space for peak voxel within the cluster
g
Family wise error corrected at the cluster level
All listed brain regions are part of the same single cluster of contiguous voxels.
All results significant at p < .05, cluster-level family-wise error correction
OFC: orbitofrontal cortex; IFC: inferior frontal cortex; PFC: prefrontal cortex; ACC: anterior cingulate cortex