Table 1.
Cysteine-Containing Peptides Identified from the Skin Secretion of B. variegata
| Monoisotopic mass (Da) a | NMD | NIS | Number of SS-links | Amino acid sequence b, c | Identity or similarity | Ref. |
|---|---|---|---|---|---|---|
| 1557.732 | 0.47 | 0.66 | 1 | DLCTFTSPGKVKCY-amide | Novel | |
| 2111.971 | 0.46 | 0.68 | 1 | ATHNMHWHRKPCNGPLLC | Similar to Kininogen-2-associated peptide | [28] |
| 2272.856 | 0.38 | 0.65 | 1 | FNQEDCFHEYLQNDAYCH | Novel | |
| 2299.091 | 0.47 | 0.71 | 2 | LYNALWPCKHCNKCKPGLLC | Similar to Kininogen-1-associated peptide | [25, 28] |
| 2329.882 | 0.38 | 0.67 | 1 | GFNQEDCFHEYIQNDAYCH | Novel | |
| 2493.259 | 0.50 | 0.65 | 1 | FKAPYNIHWHCKPGLLCKNIN | Similar to Kininogen-2-associated peptide | [28] |
| 3034.483 | 0.48 | 0.66 | 1 | LKYLYWPCKPGMPCENVD(898.477) | Kininogen-2-associated peptide | [28] |
| 3803.893 | 0.50 | 0.65 | 1 | LGSE(385.245)LKYLYWPCKPGM(1554.735) | Kininogen-2-associated peptide | [28] |
| 3212.546 | 0.48 | 0.65 | 1 | DMYELKGYKSAHGRPRVCPPGEQCPLWV-amide | Similar Bradykinin inhibitor peptide DV-28 | [29] |
| 3469.924 | 0.55 | 0.63 | 1 | Chain 1: LQSLHKLRWPGKPLLLCENENGKLRPL-amide Chain 2: CLS |
Novel | |
| 3541.942 | 0.54 | 0.62 | 1 | Chain 1: LQSLHKLRWPGKPLLLCENENEKLRPL-amide Chain 2: CLS |
Novel | |
| 6413.914 | 0.46 | 0.69 | 10 | NFVCPPQGS(5494.6008) | Similar to BSTI | [27, 30] |
| 6524.986 | 0.46 | 0.68 | 10 | NFVCPPQGS(5605.6698) | Similar to BSTI | [27, 30] |
| 7163.294 | 0.46 | 0.68 | 8 | Chain 1: LKCNTLEGRGVQATLCPPGKETCMTHSVLLNGNTNLMKGCATFSRCS Chain 2: SVGSNRLSESLYCCNLNLCN |
Novel | |
| 8159.709 | 0.46 | 0.66 | 10 | AVLTGT(374.138)DVQCGSGTCCATSVWS(5668.750) | Similar to Prokineticin Bv8 | [26] |
a Measured monoisotopic masses of unreduced peptide
b Sequences are given with all leucines; exact distinction between leucine and isoleucine could not be made
c In cases where only partial sequence could be derived, remaining masses are given in parentheses