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. 2015 Nov 20;7:122. doi: 10.1186/s13073-015-0237-0

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© Kanduri et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Th1- and Th2- specific genes and their associated epigenetic marks in the human genome. Heatmap showing gene expression and epigenetic profiles of Th1- and Th2-specific genes in T-helper subsets. The figure shows both high confidence and novel genes. Rows were first ordered based on log2 fold change and then by expression value. Normalized expression from sequencing data was standardized using Z-score for visualization purposes. In the case of H3K4me1 and H3K4me3 marks, the ratio of tag counts at the transcription start site between Th1 and Th2 is shown