Table 1.
Patient characteristics
| Characteristics | Data |
|---|---|
| Patients with GPA, n | 28 |
| Male/female, n | 16/12 |
| Age, yr, mean ± SD (range) | 61.8 ± 16.6 (30–81) |
| Patients with active GPA (BVAS >0), n (%) | 11/28 (39 %) |
| BVAS (of active GPA), mean ± SD | 6.8 ± 7.5 |
| Patients with inactive GPA (BVAS = 0), n (%) | 17/28 (61 %) |
| Duration of remission, yr (of inactive GPA), median ± SD | 4.08 ± 2.3 |
| Organ system involvement, n (%) | |
| ENT | 23/28 (82 %) |
| Lung | 15/28 (54 %) |
| Kidney | 18/28 (64 %) |
| Skin | 8/28 (29 %) |
| Joints | 12/28 (43 %) |
| NS | 8/28 (29 %) |
| Localized GPA (upper airways and ENT organs only), n (%) | 3/28 (11 %) |
| Generalized GPA, n (%) | 25/28 (89 %) |
| Number of involved organ systems, mean ± SD | 4.3 ± 1.2 |
| Number of relapses, mean ± SD (range) | 1.1 ± 1.4 (0–5) |
| Length of time since disease onset, yr, mean ± SD | 9.4 ± 7.9 |
| c-ANCA, n (%) | |
| Positive | 22/28 (79 %) |
| Negative | 3/28 (11 %) |
| Not determinable | 3/28 (11 %) |
c-ANCA cytoplasmic antineutrophil cytoplasmic antibodies, GPA granulomatosis with polyangiitis, ENT ear, nose, and throat, NS nervous system, PR3 anti-proteinase 3 antibody, SD standard deviation