Fig. 8.

The allele frequency spectrum of SNPs in expressed T. hominis transcripts suggests a diploid phase to the parasite lifecycle. a The allele frequency spectrum (reference and alternative alleles) for T. hominis SNPs. The clear peak at an allele frequency of 0.5 suggests that T. hominis is diploid. b Allele frequency spectra with synonymous and non-synonymous SNPs plotted separately. The distributions are similar, providing no evidence for reduced expression of non-synonymous alleles