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. 2015 Nov 20;46:135. doi: 10.1186/s13567-015-0275-z

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© Lacasta et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Specific immune responses induced by E75CV1 (experiment 1). Two groups of four pigs were intramuscularly inoculated with 10⁴ HAU₅₀ E75CV1 or were left as non-immunized controls. The kinetics of the individual specific antibody induction was monitored by ELISA. Average and standard deviation values are shown (A). At day 28 pi sera from the 10⁴ HAU₅₀ immunized animals were additionally subjected to an infection inhibition assay in vitro (B) and ASFV-specific T-cells were measured at day 28 pi by an IFNγ-ELISPOT assay. Average values and standard deviation shown correspond to three individual experiments for the E75CV1-vaccinated (1–4) and control animals (C1–C4) (C).