Table 3.
Prevalences, tetrachorics, case-wise concordance rates, heritability, biometric models and chi-squared test statistics
| Model | MZ prevalence | DZ prevalence | MZr | DZr | MZcw | DZcw | Heritability | Variance component estimates | Chisquare test statistics | AIC | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | D | C | E | LL | Chisquare | df | p | |||||||||
| Men | ||||||||||||||||
| Saturated | 0.06 | 0.06 | 0.80 (0.57–0.91) | 0.41 (0.09–0.65) | 0.51 (0.33–0.70) | 0.21 (0.10–0.40) | 0.78 (0.07–0.99) | – | – | – | – | –621.44 | 6 | 1254.88 | ||
| ACE | 0.06 | 0.06 | 0.80 (0.57–0.91) | 0.41 (0.09–0.65) | 0.51 (0.33–0.70) | 0.21 (0.10–0.40) | 0.78 (0.07–0.99) | 0.78 (0.07–0.99) | – | 0.02 (0.00–1.0) | 0.20 (0.08–0.41) | –621.44 | 6 | 1254.88 | ||
| ADE | 0.06 | 0.06 | 0.80 (0.58–0.91) | 0.40 (0.32–0.47) | 0.51 (0.34–0.69) | 0.21 (0.16–0.26) | 0.80 (0.60–0.91) | 0.80 (0.60–0.91) | 0.00 (0.00–1.00) | – | 0.20 (0.09–0.40) | 1255.30 | ||||
| AE | 0.06 | 0.06 | 0.80 (0.58–0.91) | 0.40 (0.32–0.47) | 0.51 (0.34–0.69) | 0.21 (0.16–0.26) | 0.80 (0.60–0.91) | 0.80 (0.60–0.91) | – | – | 0.20 (0.09–0.40) | –621.65 | 0.42 | 2 | 0.81 | |
| CE | 0.07 | 0.07 | 0.63 (0.44–0.76) | 0.63 (0.44–0.76) | 0.37 (0.26–0.50) | 0.37 (0.26–0.50) | – | – | – | 0.63 (0.46–0.77) | 0.37 (0.23–0.54) | –2921.4 | 4600 | 2 | <0.0001 | |
| Women | ||||||||||||||||
| Saturated | 0.06 | 0.06 | 0.72 (047–0.87) | 0.46 (0.15–0.69) | 0.42 (0.25–0.61) | 0.23 (0.11–0.43) | 0.52 (0.07–0.94) | – | – | – | – | –621.44 | 6 | 1254.88 | ||
| ACE | 0.06 | 0.06 | 0.72 (0.47–0.87) | 0.46 (0.15–0.69) | 0.42 (0.25–0.61) | 0.23 (0.11–0.43) | 0.52 (0.07–0.94) | 0.52 (0.07–0.94) | – | 0.20 (0.006–0.91 | 0.28 (0.13–0.50) | –621.44 | 6 | 1254.88 | ||
| ADE | 0.06 | 0.06 | 0.74 (0.52–0.87) | 0.37 (0.28–0.45) | 0.44 (0.28–0.61) | 0.18 (0.14–0.24) | 0.74 (0.54–0.87) | 0.74 (0.54–0.87) | 0.00 (0.00–1.00) | 0.26 (0.13–0.46) | 1255.30 | |||||
| AE | 0.06 | 0.06 | 0.74 (0.52–0.87) | 0.37 (0.28–0.45) | 0.44 (0.28–0.61) | 0.18 (0.14–0.24) | 0.74 (0.54–0.87) | 0.74 (0.54–0.87) | – | – | 0.26 (0.13–0.46) | –621.65 | 0.42 | 6 | 0.81 | |
| CE | 0.07 | 0.07 | 0.66 (0.48–0.79) | 0.66 (0.48–0.79) | 0.37 (0.26–0.50) | 0.37 (0.26–0.50) | – | – | – | 0.66 (0.50–0.79) | 0.34 (0.21–0.50) | –2921.4 | 4600 | 2 | <0.0001 | |
| Sex-adjusted | ||||||||||||||||
| Saturated | 0.06 | 0.06 | 0.68 (0.55–078) | 0.45 (0.23–0.62) | 0.39 (0.30–0.50) | 0.23 (0.14–0.36) | 0.47 (0.12–0.85) | – | – | – | – | –806.7 | 2 | 1621.34 | ||
| ACE | 0.06 | 0.06 | 0.68 (0.55–0.78) | 0.45 (0.23–0.62) | 0.39 (0.30–0.50) | 0.23 (0.14–0.36) | 0.47 (0.12–0.85) | 0.47 (0.12–0.85) | – | 0.22 (0.02–0.76) | 0.31 (0.21–0.44) | –806.7 | – | 4 | 1621.34 | |
| ADE | 0.06 | 0.06 | 0.70 (0.57–0.80) | 0.35 (0.29–0.40) | 0.41 (0.31–0.51) | 0.18 (0.15–0.21) | 0.70 (0.58–0.79) | 0.70 (0.58–0.80) | 0.00 (0.00–0.00) | – | 0.30 (0.21–0.42) | 1622.31 | ||||
| AE | 0.06 | 0.06 | 0.70 (0.58–0.79) | 0.35 (0.29–0.40) | 0.41 (0.31–0.51) | 0.18 (0.15–0.21) | 0.70 (0.58–0.79) | 0.70 (0.58–0.79) | – | – | 0.30 (0.21–0.42) | –807.2 | 0.97 | 1 | 0.325 | |
| CE | 0.07 | 0.07 | 0.62 (0.51–0.71) | 0.62 (0.51–0.71) | 0.37 (0.29–0.45) | 0.37 (0.29–0.45) | – | – | – | 0.62 (0.52–0.72) | 0.38 (0.28–0.48) | –2913.8 | 4214 | 1 | <0.0001 | |
A Additive genetic, AIC Akaiki’s information criterion, C Common environment, D Dominant genetic, DZcw Dizygotic case-wise concordance rate, DZr Dizygotic correlation, E Unique environment, MZcw Monozygotic case-wise concordance rate, MZr Monozygotic correlation, Saturated Saturated model not including censoring