Table 1.

Optimal designs for standard parameterization

Model	Log dose 1	Log dose 2	Log dose 3	Log dose 4
Log-logistic	−5	−1	1	5
Log-normal	−5	−0.7	0.7	5
Weibull	−5	−1	0.5	5

Dose levels for all three models and the standard parameterization c = 0, d = 1, b = 1 and e = 1. All dose levels are to be used for 25 % of replicates

Dose levels are independent of c and d

Transformation of log doses for general “b” or “e”: $log\left(x_{new}\right)=log\left(e\right)+\frac{1}{b}log\left(x_{\text{standard}}\right)$