Table 2.

Significant predictors of eGFR at different time points of late posttransplant period^∗.

Predictive variables	Univariate linear regression			Multivariate linear regression
	Beta	SE	P value	Beta	SE	P value
eGFR at baseline (mL/min/1.73 m2), N = 79
Log proteinuria/creatinine†	−0.488	0.104	<0.001	−0.406	0.153	0.012
Impaired initial function‡	−0.235	0.112	0.040
Log mean arterial pressure†	−0.502	0.099	<0.001	−0.332	0.153	0.037
Previous acute rejection‡	−0.241	0.112	0.035
eGFR after 1 year of follow-up (mL/min/1.73 m2), N = 79
eGFR at baseline	0.870	0.057	<0.001	0.721	0.091	<0.001
Log proteinuria/creatinine†	−0.476	0.105	<0.001
Serum β2MG	−0.538	0.137	<0.001	−0.291	0.091	0.003
Impaired initial function‡	−0.233	0.113	0.042
Log mean arterial pressure†	−0.436	0.103	<0.001
Time after transplantation	−0.262	0.111	0.021
eGFR after 2 years of follow-up (mL/min/1.73 m2), N = 71
eGFR at baseline	0.838	0.063	<0.001	0.649	0.101	<0.001
Log proteinuria/creatinine†	−0.473	0.105	<0.001
Serum β2MG	−0.527	0.138	<0.001	−0.302	0.098	0.004
Impaired initial function‡	−0.230	0.113	0.030
Log mean arterial pressure†	−0.447	0.103	<0.001
Time after transplantation	−0.332	0.108	0.003	−0.148	0.097	0.135
Previous acute rejection‡	−0.261	0.112	0.023

β2MG: β2-microglobulin; eGFR: estimated glomerular filtration rate; beta: standardized regression coefficient; SE: standard error of beta; N: number of patients investigated; ^∗only variables that significantly influenced the eGFR in univariate analysis are included; ^†natural log-transformed variables; ^‡impaired initial function and acute rejection scored in points.