Table 3.
Significant predictors of eGFR decline by ≥25% after one and two years of follow-up∗.
| Predictive variables | Univariate logistic regression | Multivariate logistic regression | ||||
|---|---|---|---|---|---|---|
| OR | CI | P value | OR | CI | P value | |
| eGFR decline by ≥25% after 1 year of follow-up, N = 10 | ||||||
| Proteinuria/creatinine | 1.03 | 1.00–1.07 | 0.038 | 1.03 | 0.99–1.07 | 0.158 |
| Serum β2MG | 1.51 | 1.10–2.07 | 0.010 | 1.54 | 1.05–2.26 | 0.025 |
| Previous acute rejection | 4.82 | 1.12–20.84 | 0.032 | 2.24 | 0.36–13.85 | 0.378 |
|
| ||||||
| eGFR decline by ≥25% after 2 years of follow-up, N = 12 | ||||||
| Serum β2MG | 1.36 | 1.06–1.76 | 0.016 | 1.41 | 1.06–1.87 | 0.016 |
| Time after transplantation | 1.02 | 1.00–1.03 | 0.006 | 1.02 | 1.00–1.03 | 0.006 |
β2MG: β2-microglobulin; eGFR: estimated glomerular filtration rate; OR: odds ratio; CI: 95% confidence interval; N: number of patients with certain decline in eGFR; ∗only variables that significantly influenced the eGFR decline in univariate analysis are included.