TABLE 1.
Characteristics of the Patients With Biliary Cystadenoma and Cystadenocarcinoma
| Total (n = 248) | BCA (n = 221, 89.1%) | BCAC (n = 27,10.9%) | P | |
|---|---|---|---|---|
| Demographics | ||||
| Age, mean (SD), yr | 52.1 (15.1) | 51.2 (15.1) | 58.9 (13.3) | 0.012 |
| Female, n (%) | 215 (86.7) | 199 (90.0) | 16 (59.3) | <0.001 |
| Race, White, n (%) | 219 (88.3) | 193 (87.3) | 26 (96.3) | 0.346 |
| Symptom, n (%) | 214 (86.3) | 189 (85.5) | 25 (92.6) | 0.313 |
| Abdominal pain | 142 (57.3) | 128 (57.9) | 14 (51.9) | 0.547 |
| Abdominal fullness | 50 (20.2) | 40 (18.1) | 10 (37.0) | 0.021 |
| Early satiety | 31 (12.5) | 29 (13.1) | 2 (7.4) | 0.397 |
| Weight loss | 9 (3.6) | 8 (3.6) | 1 (3.7) | 0.982 |
| Jaundice | 28 (11.3) | 25 (11.3) | 3 (11.1) | 0.975 |
| Asymptomatic | 34 (13.7) | 32 (14.5) | 2 (7.4) | 0.313 |
| Preoperative laboratory data | ||||
| Total Bilirubin (mg/dL), median (IQR) | 0.6 (0.4–0.8) | 0.6 (0.4–0.7) | 0.7 (0.5–1.0) | 0.844 |
| CA 19–9 (U/mL), median (IQR) (n = 210) | 15 (7.1–94.0) | 15 (6.0–63.1) | 210 (37.1–280.0) | 0.647 |
| CEA (ng/mL), median (IQR) (n = 210) | 2.7 (1.0–4.6) | 2.4 (0.9–4.6) | 4.3 (1.9–90.0) | <0.001 |
| ALT (U/L), median (IQR) | 27.0 (17.5–45.5) | 27.0 (18.0–48.0) | 20.5 (17.0–37.0) | 0.355 |
| Preoperative imaging, n (%) | ||||
| CT | 155 (62.5) | 137 (62.0) | 18 (66.7) | 0.175 |
| MRI | 17 (6.9) | 17 (7.7) | 0 (0) | |
| CT + MRI | 46 (18.5) | 39 (17.6) | 7 (25.9) | |
| USG | 145 (58.5) | 128 (57.9) | 17 (63.0) | 0.373 |
| Endoscopic retrograde pancreatography | 40 (16.1) | 36 (16.3) | 4 (14.8) | 0.872 |
| Preoperative image finding features (any of below), n (%) | 197 (79.4) | 175 (79.2) | 22 (81.5) | 0.781 |
| Multilocular cyst | 141 (56.9) | 123 (55.7) | 18 (66.7) | 0.093 |
| Septa | 163 (65.7) | 145 (65.6) | 18 (66.7) | 0.913 |
| Mural nodularity | 41 (16.5) | 24 (10.9) | 17 (63.0) | <0.001 |
| Calcification | 25 (10.1) | 16 (7.2) | 9 (33.3) | <0.001 |
| Hypervascular | 19 (7.7) | 10 (4.5) | 9 (33.3) | <0.001 |
| Enhancement after contrast | 42 (16.9) | 31 (14.0) | 11 (40.7) | <0.001 |
| Biliary ductal dilatation | 44 (17.7) | 36 (16.3) | 8 (29.6) | 0.087 |
| Primary cystic tumor | ||||
| Number of cystic lesions, mean (SD) | 1.3 (0.8) | 1.4 (0.8) | 1.5 (0.8) | 0.445 |
| Biliary cyst size (cm), median (IQR) | 10 (7–13) | 10 (7–12) | 10.5 (7–15) | 0.338 |
| Intrahepatic Location | ||||
| Left | 108 (43.5) | 98 (44.3) | 10 (37.0) | 0.033 |
| Right | 76 (30.6) | 62 (28.1) | 14(51.9) | |
| Both | 50 (20.2) | 48 (21.7) | 2 (7.4) |
Bold values highlight comparisons which reached statistical significance since p < .05.