Table 1. Gene expression (up-regulated by C/EBPA-saRNA).
Clustered analysis of genes positively regulated following transfection of C/EBPα-saRNA in HepG2 cells.
| Gene Symbol | Fold Up-Regulation | T-TEST |
|---|---|---|
| C/EBPAsaRNA/Control Group | p value | |
| BAX | 1.12 | 0.0027 |
| BID | 13.58 | 0.0001 |
| CASP8 | 6.69 | 0.0000 |
| DAB2IP | 2.59 | 0.0042 |
| DLC1 | 4.84 | 0.0001 |
| FAS | 1.64 | 0.0004 |
| FHIT | 2.84 | 0.0021 |
| GADD45B | 3.35 | 0.0001 |
| HHIP | 1.59 | 0.0054 |
| IGF2 | 9.75 | 0.0001 |
| LEF1 | 17.86 | 0.0001 |
| PTEN | 1.28 | 0.0013 |
| PTK2 | 2.87 | 0.0001 |
| RB1 | 1.96 | 0.0001 |
| RUNX3 | 6.01 | 0.0002 |
| SMAD4 | 1.72 | 0.0019 |
| SOCS3 | 6.52 | 0.0003 |
| TGFBR2 | 3.71 | 0.0025 |
| TNFSF10 | 3.53 | 0.0003 |
| P53 | 3.91 | 0.0018 |