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. Author manuscript; available in PMC: 2015 Nov 22.
Published in final edited form as: Hepatology. 2013 Dec 9;59(1):216–227. doi: 10.1002/hep.26669

Table 2. Gene expression (down-regulated by C/EBPA-saRNA).

Clustered analysis of genes negatively regulated following transfection of C/EBPα-saRNA in HepG2 cells.

Gene Symbol Fold Down-Regulation T-TEST

C/EBPAsaRNA/Control Group p value

ADAM17 −2.19 0.0007
AKT1 −1.78 0.0220
ANGPT2 −1.61 0.0097
BCL2 −2.77 0.0177
BCL2L1 −1.77 0.0014
BIRC2 −2.83 0.0054
BIRC5 −18.53 0.0014
CCL5 −35.1 0.0001
CCND1 −6.45 0.0001
CCND2 −2.40 0.0001
CDH1 −3.04 0.0002
CDH13 −5.52 0.0001
CDKN1A −2.53 0.0016
CDKN1B −1.74 0.0145
CDKN2A −6.75 0.0001
CFLAR −7.12 0.0003
CTNNB1 −1.59 0.0081
CXCR4 −2.73 0.0004
E2F1 −1.40 0.0174
EGF −8.63 0.0074
EGFR −2.58 0.0064
EP300 −3.28 0.0001
FADD −1.15 0.0001
FLT1 −36.26 0.0001
FZD7 −2.00 0.0004
GSTP1 −1.97 0.0019
HGF −11.07 0.0001
HRAS −3.69 0.0001
IGFBP1 −7.36 0.0001
IGFBP3 −17.56 0.0001
IRS1 −1.61 0.0010
ITGB1 −2.48 0.0001
KDR −13.5 0.0001
MCL1 −2.47 0.0031
MET −1.30 0.0247
MSH2 −1.03 0.0057
MSH3 −3.63 0.0002
MTDH −1.73 0.0014
MYC −1.76 0.0132
NFKB1 −1.48 0.0365
NRAS −29.47 0.0001
OPCML −1.51 0.0074
PDGFRA −1.54 0.0019
PIN1 −1.15 0.0012
PTGS2 −2.76 0.0001
PYCARD −1.49 0.0178
RAC1 −1.46 0.0069
RASSF1 −4.59 0.0001
RELN −2.09 0.0005
RHOA −1.46 0.0019
SFRP2 −1.73 0.0092
SMAD7 −3.46 0.0002
SOCS1 −7.04 0.0001
STAT3 −13.06 0.0006
TCF4 −9.96 0.0008
TERT −1.65 0.0005
TGFA −9.27 0.0001
TGFB1 −1.80 0.0002
TLR4 −4.81 0.0007
TNFRSF10B −1.07 0.0063
VEGFA −1.30 0.0429
WT1 −6.674 0.0010
XIAP −2.93 0.0228
YAP1 −1.58 0.0058