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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Neuropharmacology. 2015 Aug 13;99:491–499. doi: 10.1016/j.neuropharm.2015.08.017

Figure 7. Effects of SKF81297 on SFK and NMDA receptor expression and phosphorylation in the PSD of rat striatal neurons.

Figure 7

(A) Effects of SKF81297 (SKF) on Fyn and Src expression and Y416 phosphorylation in the PSD. Note that SKF81297 enhanced Fyn expression and Y416 phosphorylation. (B) Effects of SKF81297 on NMDA receptor subunit expression and Y1472 phosphorylation in the PSD. Note that SKF81297 enhanced GluN1 and GluN2B expression and Y1472 phosphorylation. Representative immunoblots are shown left to the quantified data. Rats were given an injection of SKF81297 (3 mg/kg, i.p.) and sacrificed 45 min after SKF81297 injection for biochemical fractionation of PSD proteins. Data are presented as means ± SEM (n = 4 per group). *P < .05 versus saline (Mann-Whitney test).