Table 1.

In this table, from left to right, the following columns are reported: the number of patients, mean age of study population (in case of more than one group of patients, more mean ages are reported and compared), diabetes (diabetic diseases, yes or no), D. patients (number of diabetic patients), insulin therapy (insulin therapy, yes or no), and references, in alphabetic order with first name of authors and assigned numbers. The symbol — is used in case of information not found in the reference studies.

Number of patients	Mean age	Diabetes	D. patients	Insulin therapy	References
170	59 ± 9 versus 76 ± 4	—	—	—	Bleeker et al. [13]
813	66.4	Yes	207	Yes	Cleland et al. (CARE-HF trial) [12]
355	64 ± 7 versus 62 ± 10	Yes	141	Yes	Fantoni et al. [19]
330	83.7 ± 2.6 versus 66.9 ± 9.5	—	—	—	Foley et al. [16]
1787	<65 versus 65–74 versus ≥75	Yes	26 (5%) versus 55 versus (7%) 27 (6%)	Yes	Fumagalli et al. [15]
552	67 ± 9 versus 63 ± 10	Yes	552	Yes	George et al. [20]
813	—	Yes	207	Yes	Hoppe et al. [21]
447	65.4 ± 10.2 versus 66.6 ± 7.5	Yes	91	Yes	Mangiavacchi et al. [22]
1820	65	Yes	552	Yes	Martin et al. (MADIT-CRT) [11]
1500	66 ± 14	Yes	481	—	Ruwald et al. (MADIT-RIT) [23]
610	61.8 ± 11.6 versus 62.9 ± 10.6	Yes	46 versus 91	—	Gold et al. (REVERSE) [10]
3327	<70 versus >70	—	—	—	Pulignano et al. [14]
72	81.4 ± 5.8 versus 82.5 ± 6.9	Yes	32	Yes	Sardu et al. [24]