Table 1.

Molecular structure of mature GnIH peptides in chordates.

Chordates	Peptide name	Molecular structure	Reference
Mammals	human RFRP-1	MPHSFANLPLRFa	Ubuka et al. (43)
	human RFRP-3	VPNLPQRFa	Ubuka et al. (43)
	macaque RFRP-3	SGRNMEVSLVRQVLNLPQRFa	Ubuka et al. (44)
	bovine RFRP-1	SLTFEEVKDWAPKIKMNKPVVNKMPPSAANLPLRFa	Fukusumi et al. (45)
	bovine RFRP-3	AMAHLPLRLGKNREDSLSRWVPNLPQRFa	Yoshida et al. (46)
	rat RFRP-3	ANMEAGTMSHFPSLPQRFa	Ukena et al. (47)
	Siberian hamster RFRP-1	SPAPANKVPHSAANLPLRFa	Ubuka et al. (48)
	Siberian hamster RFRP-3	TLSRVPSLPQRFa	Ubuka et al. (48)
Birds	quail GnIH	SIKPSAYLPLRFa	Tsutsui et al. (18)
	quail GnIH-RP-2	SSIQSLLNLPQRFa	Satake et al. (40)
	chicken GnIH	SIRPSAYLPLRFa	McConn et al. (39)
	European starling GnIH	SIKPFANLPLRFa	Ubuka et al. (41)
	zebra finch GnIH	SIKPFSNLPLRFa	Tobari et al. (42)
Reptiles	red-eared slider GnIH	SIKPVANLPLRFa	Ukena et al. (49)
	red-eared slider GnIH-RP-1	STPTVNKMPNSLANLPLRFa	Ukena et al. (49)
	red-eared slider GnIH-RP-2	SSIQSLANLPQRFa	Ukena et al. (49)
Amphibians	bullfrog GRP/R-RFa	SLKPAANLPLRFa	Koda et al. (50) and Chartrel et al. (51)
	bullfrog GRP-RP-1	SIPNLPQRFa	Ukena et al. (52)
	bullfrog GRP-RP-2	YLSGKTKVQSMANLPQRFa	Ukena et al. (52)
	bullfrog GRP-RP-3	AQYTNHFVHSLDTLPLRFa	Ukena et al. (52)
	red-bellied newt LPXRFa-1	SVPNLPQRFa	Chowdhury et al. (53)
	red-bellied newt LPXRFa-2	MPHASANLPLRFa	Chowdhury et al. (53)
	red-bellied newt LPXRFa-3	SIQPLANLPQRFa	Chowdhury et al. (53)
	red-bellied newt LPXRFa-4	APSAGQFIQTLANLPQRFa	Chowdhury et al. (53)
Teleost fishes	goldfish LPXRFa-3	SGTGLSATLPQRFa	Sawada et al. (54)
Agnathans	sea lamprey LPXRFa-1a	SGVGQGRSSKTLFQPQRFa	Osugi et al. (55)
	sea lamprey LPXRFa-1b	AALRSGVGQGRSSKTLFQPQRFa	Osugi et al. (55)
	sea lamprey LPXRFa-2	SEPFWHRTRPQRFa	Osugi et al. (55)
Protochordates	amphioxus PQRFa-1	WDEAWRPQRFa	Osugi et al. (56)
	amphioxus PQRFa-2	GDHTKDGWRPQRFa	Osugi et al. (56)
	amphioxus PQRFa-3	GRDQGWRPQRFa	Osugi et al. (56)

Only structurally determined mature endogenous peptides are shown.