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. 2015 Nov 21;386(10008):2059–2068. doi: 10.1016/S0140-6736(15)00257-3

Table 4.

Home systolic blood pressure dose response (higher vs lower dose)

Blood pressure (mm Hg) p value
Spironolactone −3·86 (−5·28 to −2·45) <0·0001
Doxazosin −0·88 (−2·32 to 0·56) 0·23
Bisoprolol −1·49 (−2·94 to −0·04) 0·04
Placebo −0·68 (−2·10 to 0·75) 0·35

Difference in mean home systolic blood pressure after treatment with the lower (week 6) and higher doses (week 12) of each treatment.