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. 2015 Nov 23;5:16940. doi: 10.1038/srep16940

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Copyright © 2015, Macmillan Publishers Limited

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Hearts of WT and P2×7^−/− mice, immunized with pcDNA3 or pcDNA3 M2AChR, were collected and analyzed at 40 weeks post-immunization. Upper panel: (A–D) Representative LV myocardial cross section micrographs of hearts from animals of each group at 40 weeks post-immunization. Scale bar, 2 cm. Lower panel: (E) Left Ventricle (LV) area ratio between the area of the cross-section of lumen and the total area of the cross-section of the heart. Black bars represent M₂AChR groups and white bars pcDNA3 groups. The letter a indicates a comparison between the WT pcDNA3 and WT M₂AChR groups, while letter b indicates a comparison between the P2×7^−/− pcDNA3 and P2×7^−/− M₂AChR groups. N = 5, p < 0.05 was considered statistically significant.