Table 2. Electrocardiogram recordings in mice that received pcDNA3 or M2AChR WT serum 10 weeks post-serum transfer.
Wild Type Recipient | P2×7−/−Recipient | pcDNA3 Wild type serum | M2AChR Wild type serum | |
---|---|---|---|---|
pcDNA3 Wild type serum | M2AChR Wild type serum | |||
RR Interval (ms) | 210.45 ± 45.60 | 138.97 ± 10.53a | 147.70 ± 21.24c | 168.77 ± 27.33 |
Heart Rate (BPM) | 337.20 ± 81.22 | 379.23 ± 13.70 | 384.23 ± 52.29c | 359.15 ± 55.39 |
PR Interval (ms) | 40.44 ± 8.55 | 34.84 ± 8.68 | 39.13 ± 1.48 | 40.10 ± 0.45 |
QRS Interval (ms) | 9.63 ± 1.37 | 13.21 ± 1.25 | 13.86 ± 1.97 | 13.86 ± 1.52 |
QTc Interval (ms) | 66.68 ± 1.13 | 85.43 ± 2.08 | 83.39 ± 2.91 | 74.89 ± 2.52 |
ST Height (mV) | 0.020 ± 0.054 | 0.115 ± 0.057 | −0.050 ± 0.022 | - 0.015 ± 0.070d |
JT interval | 12.91 ± 1.14 | 19.07 ± 0.76a | 16.88 ± 6.85 | 12.24 ± 2.92d |
Comparison between WT pcDNA3 and WT M2AChR and between P2×7−/− pcDNA3 and P2×7−/− M2AChR are marked with the letters a and b, respectively. Comparison between WT pcDNA3 and P2×7−/− pcDNA3 and between WT M2AChR and P2×7−/− M2AChR are marked by the letter c and d, respectively. p < 0.05 was considered statistically significant difference. N = 5.