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. 2015 Nov 23;5:16706. doi: 10.1038/srep16706

Figure 3. Amino acid (aa) sequence alignment (1-235 aa) for LMP-1 proteins (387 aa) deduced from genomes of BL-EBVs and EBVs available in NCBI database.

Figure 3

There are overall 22 common aa changes observed in LMP-1 protein from BL-EBVs. Positions of the 9 out of the 22 common aa changes uniquely shared by the similar 11 BL-EBVs studied, but not VGO, are marked with purple dots (E2D, H3L, S57A, I63V, I124V, I152L, H213N and E214Q). Positions of the 8 aa out of the 13 common aa changes in the N-terminus are marked as red dots in this figure: L25I, D46N, I85L, F106Y, L126F, M129I, L151I and G212S. These changes were also present in essentially all NPC-EBVs. The other 5 common aa changes observed in all 12 BL-EBVs and essentially all NPC-EBVs are not shown in the Figure: S309N, Q322N, Q334R, L338S and S366T.