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. 2015 Nov 23;5:17047. doi: 10.1038/srep17047

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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HepG2/NTCPA3 cells were infected with HBV at 1,000 GEq/Cell. Simvastatin or proscillaridin A was added to the culture supernatant at 3 dpi. The resulting cells were harvested at 6 dpi. The amount of intracellular HBV RNA was quantified by real-time qRT-PCR (black bars) and is presented as the percentage of the control value (DMSO). Cell viability was evaluated (gray bars). Data were calculated from 3 to 5 independent experiments and are expressed as means ± SD.