Table 1. Anti-HBV activities of chemical compounds.
Compounds | IC50 | CC50 | Selectivity Index |
---|---|---|---|
Simvastatin | 5.2 ± 0.6 μM | >30 μM | ND |
Fluvastatin | >30 μM | >100 μM | ND |
Proscillaridin A | 7.2 ± 2.5 nM | 495.9 ± 140.1 nM | 75.5 ± 26.7 |
Bufalin | 32.4 ± 11.3 nM | 478.6 ± 64.7 nM | 15.8 ± 4.3 |
Convallatoxin | 10.7 ± 3.6 nM | 155.7 ± 53.8 nM | 15.7 ± 4.7 |
Digitoxin | 93.3 ± 15.3 nM | 1727.0 ± 384.2 nM | 18.9 ± 3.4 |
Digoxin | >100 nM | 1429.3 ± 276.6 nM | ND |
Azelastine | >30 μM | >30 μM | ND |
ND: not determined.