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. 2015 Nov 23;5:17047. doi: 10.1038/srep17047

Table 1. Anti-HBV activities of chemical compounds.

Compounds IC50 CC50 Selectivity Index
Simvastatin 5.2 ± 0.6 μM >30 μM ND
Fluvastatin >30 μM >100 μM ND
Proscillaridin A 7.2 ± 2.5 nM 495.9 ± 140.1 nM 75.5 ± 26.7
Bufalin 32.4 ± 11.3 nM 478.6 ± 64.7 nM 15.8 ± 4.3
Convallatoxin 10.7 ± 3.6 nM 155.7 ± 53.8 nM 15.7 ± 4.7
Digitoxin 93.3 ± 15.3 nM 1727.0 ± 384.2 nM 18.9 ± 3.4
Digoxin >100 nM 1429.3 ± 276.6 nM ND
Azelastine >30 μM >30 μM ND

ND: not determined.